Structural brain improvements following individually tailored serious exergame-based training in mild neurocognitive disorders: exploratory randomized controlled trial

Patrick Manser, Michael Rosio, André Schmidt, Lars Michels, Eling D. de Bruin

Alzheimer's Research & Therapy, vol. 17(1), 2025 Sep 8, p. 190

Beyond “just” fun: The role of exergames in advancing health promotion and disease prevention

Patrick Manser, Eling D. de Bruin, Jean-Jacques Temprado, Louis Bherer, Fabian Herold

Neuroscience & Biobehavioral Reviews, vol. 176, 2025 Jun 21, p. 106260

“Brain-IT”: Exergame training with biofeedback breathing in neurocognitive disorders

Patrick Manser, Eling D. de Bruin

Alzheimer's & Dementia, vol. 20, 2024, pp. 4747-4764

Components of effective exergame-based training to improve cognitive functioning in middle-aged to older adults – A systematic review and meta-analysis

Patrick Manser, Fabian Herold, Eling D. de Bruin

Ageing Research Reviews, vol. 99, 2024, p. 102385

Making the Best Out of IT: Design and Development of Exergames for Older Adults With Mild Neurocognitive Disorder – A Methodological Paper

Patrick Manser, Eling D. de Bruin

Frontiers in Aging Neuroscience, vol. 13, 2021

Beyond FITT: addressing density in understanding the dose–response relationships of physical activity with health—an example based on brain health

Fabian Herold, Liye Zou, Paula Theobald, Patrick Manser, Ryan S Falck, Qian Yu, Teresa Liu-Ambrose, Charles H Hillman, Arthur K Kramer, Kirk I Erickson, Boris Cheval, Yanxia Chen, Matthew Heath, Zhihao Zhang, Toru Ishihara, Keita Kamijo, Soichi Ando, Yanping Gao, Joseph T. Costello, Meijun Hou, Mats Hallgren, Zhihui Chen, David Moreau, Vahid Farrahi, David A. Raichlen, Emmanuel Stamatakis, Michael J. Wheeler, Neville Owen, Sebastian Ludyga, Henning Budde, Thomas Gronwald

European Journal of Applied Physiology, Jun 26

Co-Develop-IT - Co-design, Development, and Evaluation of Individually Tailored Technology-Enhanced Training and Rehabilitation Concepts: Methodological Guideline Development Study

Patrick Manser, Lotte E.S. Hardeman, Andreas Wallin, David Moulaee Conradsson, Breiffni Leavy, Franziska Albrecht, Melvyn Roerdink, Jean-Jacques Temprado, Eling D. de Bruin, Erika Franzén

medRxiv, 2025

Structural brain improvements following individually tailored serious exergame-based training in mild neurocognitive disorders: exploratory randomized controlled trial

Patrick Manser, Michael Rosio, André Schmidt, Lars Michels, Eling D. de Bruin

Alzheimer's Research & Therapy, vol. 17(1), 2025 Sep 8, p. 190

Beyond “just” fun: The role of exergames in advancing health promotion and disease prevention

Patrick Manser, Eling D. de Bruin, Jean-Jacques Temprado, Louis Bherer, Fabian Herold

Neuroscience & Biobehavioral Reviews, vol. 176, 2025 Jun 21, p. 106260

Domain-Specific Evaluation of Exergame Metrics Among Older Adults With Mild Neurocognitive Disorder: Secondary Analysis of 2 Randomized Controlled Trials

Wanda Kaiser, Eling D. de Bruin, Patrick Manser

JMIR Serious Games, vol. 13, 2025 May 21, pp. e65878

Diagnostic accuracy of heart rate variability as a screening tool for mild neurocognitive disorder

Julia Czopek-Rowinska, Eling D. de Bruin, Patrick Manser

Frontiers in Aging Neuroscience, vol. 16, 2024

Beyond FITT-How Density Can Improve the Understanding of the Dose-Response Relationship Between Physical Activity and Brain Health

Fabian Herold, Liye Zou, Paula Theobald, Patrick Manser, Ryan S Falck, Qian Yu, Teresa Liu-Ambrose, Charles H Hillman, Arthur K Kramer, Kirk I Erickson, Boris Cheval, Yanxia Chen, Matthew Heath, Zhihao Zhang, Toru Ishihara, Keita Kamijo, Soichi Ando, Yanping Gao, Joseph T. Costello, Meijun Hou, Mats Hallgren, Zhihui Chen, David Moreau, Vahid Farrahi, David A. Raichlen, Emmanuel Stamatakis, Michael J. Wheeler, Neville Owen, Sebastian Ludyga, Henning Budde, Thomas Gronwald

SportRxiv, Society for Transparency, Openness, and Replication in Kinesology, 2024

PEMOCS: theory derivation of a concept for PErsonalized MOtor-Cognitive exergame training in chronic Stroke—a methodological paper with an application example

Simone K. Huber, Patrick Manser, Eling D. de Bruin

Frontiers in Sports and Active Living, vol. 6, 2024

Brain-IT: Targeting the Brain using Information Technology for Secondary Prevention of mild Neurocognitive Disorder

Patrick Manser

ETH Zurich, 2024

Diagnostic accuracy, reliability, and construct validity of the German quick mild cognitive impairment screen

Patrick Manser, Eling D de Bruin

BMC geriatrics, vol. 24, Springer, 2024, p. 613

Test-retest reliability and validity of vagally-mediated heart rate variability to monitor internal training load in older adults: a within-subjects (repeated-measures) randomized study

Patrick Manser, Eling D de Bruin

BMC Sports Science, Medicine and Rehabilitation, vol. 16, Springer, 2024, p. 141

“Brain-IT”: Exergame training with biofeedback breathing in neurocognitive disorders

Patrick Manser, Eling D. de Bruin

Alzheimer's & Dementia, vol. 20, 2024, pp. 4747-4764

Components of effective exergame-based training to improve cognitive functioning in middle-aged to older adults – A systematic review and meta-analysis

Patrick Manser, Fabian Herold, Eling D. de Bruin

Ageing Research Reviews, vol. 99, 2024, p. 102385

Feasibility, usability, and acceptance of “Brain-IT”—A newly developed exergame-based training concept for the secondary prevention of mild neurocognitive disorder: a pilot randomized controlled trial

Patrick Manser, Hanna Poikonen, Eling D. de Bruin

Frontiers in Aging Neuroscience, vol. 15, 2023

Development and initial validation of the German version of the Exergame Enjoyment Questionnaire (EEQ-G)

Patrick Manser, Simone Huber, Julia Seinsche, Eling D. de Bruin, Eleftheria Giannouli

PLOS ONE, vol. 18, Public Library of Science, 2023 Jun, pp. 1-17

Effectiveness of an Individualized Exergame-Based Motor-Cognitive Training Concept Targeted to Improve Cognitive Functioning in Older Adults With Mild Neurocognitive Disorder: Study Protocol for a Randomized Controlled Trial

Patrick Manser, Lars Michels, André Schmidt, Filip Barinka, Eling D de Bruin

JMIR Res Protoc, vol. 12, 2023 Feb 6, pp. e41173

Design Considerations for an Exergame-Based Training Intervention for Older Adults With Mild Neurocognitive Disorder: Qualitative Study Including Focus Groups With Experts and Health Care Professionals and Individual Semistructured In-depth Patient Interviews

Patrick Manser, Manuela Adcock-Omlin, Eling D de Bruin

JMIR Serious Games, vol. 11, 2023 Jan 5, pp. e37616

Making the Best Out of IT: Design and Development of Exergames for Older Adults With Mild Neurocognitive Disorder – A Methodological Paper

Patrick Manser, Eling D. de Bruin

Frontiers in Aging Neuroscience, vol. 13, 2021

Can Reactivity of Heart Rate Variability Be a Potential Biomarker and Monitoring Tool to Promote Healthy Aging? A Systematic Review With Meta-Analyses

Patrick Manser, Melanie Thalmann, Manuela Adcock, Ruud H. Knols, Eling D. de Bruin

Frontiers in Physiology, vol. 12(1133), 2021